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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • Pyroxamide EI2278

    Pyroxamide是组蛋白去乙酰抑制剂HDAC (histone deacetylase)。

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  • PYZD 4409 EI2280

    PYZD 4409是Ubiquitin-activating enzyme (E1) 的抑制剂。

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  • Pyrrolidinedithiocarbamate ammonium EI2279

    Pyrrolidinedithiocarbamate ammonium是Pyrrolidinedithiocarbamate ammonium inhibits NF-κB and prevents increase in NOS mRNA.。

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  • PSI EI2265

    PSI是蛋白酶体抑制剂，可以抑制NF-κB的激活。

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  • PSN 375963 hydrochloride EI2266

    PSN 375963 hydrochloride是GPR119 受体激动剂。

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