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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • Phenobarbital sodium salt EI2156

    Phenobarbital sodium salt是加强 GABA能活性（GABAergic activity）。。

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  • PHCCC EI2153

    PHCCC是活性的 group I mGlu 拮抗剂。

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  • Phencyclidine hydrochloride EI2155

    Phencyclidine hydrochloride是非竞争性 NMDA 受体拮抗剂。

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  • Phaclofen EI2151

    Phaclofen是适度的选择性 GABAB 拮抗剂。

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  • PF 945863 EI2139

    PF 945863是大环内酯类抗生素(macrolide antibiotic)。

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