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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • PIT 1 EI2181

    PIT 1是抑制 Akt 信号通路。

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  • PK 44 phosphate EI2183

    PK 44 phosphate是活性的，选择性 dipeptidyl peptidase IV (DPP-IV) 抑制剂。

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  • PK-THPP EI2190

    PK-THPP是活性的 TASK-3 通道阻断剂。

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  • PMPA (NMDA antagonist) EI2197

    PMPA (NMDA antagonist)是竞争性 NMDA 拮抗剂。

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  • PIM-1 inhibitor 2 EI2174

    PIM-1 inhibitor 2是Pim-1 激酶抑制剂。

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