In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
Rifampicin是Pregnane X 的受体激动剂, 抗生素类。
MoreRifaximin是Pregnane X 受体激动剂, 抗生素类。
MoreRimcazole dihydrochloride是σ2 拮抗剂。 也是DAT的抑制剂。
MoreRemacemide hydrochloride是Remacemide hydrochloride is a NMDA antagonist,it blocks ion channel and allosteric modulatory site.。
MoreReversan是选择性 MRP1,P-gp 抑制剂。
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