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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    Ro 0437626是选择性P2X1拮抗剂。

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    Ro 04-5595 hydrochloride是NR2B选择性 NMDA 拮抗剂。

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  • Ro 106-9920 EI2354

    Ro 106-9920是Ro 106-9920 is a NF-κB activation inhibitor 。

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    Ro 01-6128是mGlu1阳性变构的调节剂（positive allosteric modulator）。

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    Rhosin hydrochloride是Rho GTPase inhibitor。

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