In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
Pregnenolone sulfate sodium salt是NMDA 增效剂(potentiator)。
MorePPDA是亚型选择性 NR2C/NR2D 拮抗剂。
MorePPNDS是活性的, 选择性 P2X1 拮抗剂。
MorePPPA是竞争性 NR2A 拮抗剂。
MorePNU 37883 hydrochloride是血管 Kir6 (KATP) 的通道阻断剂。
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