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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • Prostaglandin E2 EI2241

    Prostaglandin E2是主要的内源性前列腺素（prostanoid）。

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  • Prostaglandin F2α EI2242

    Prostaglandin F2α是天然前列腺素（prostanoid） 活性血管收缩剂 （vasoconstrictor）。

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  • Prostratin EI2243

    Prostratin是PKC的激动剂， 也是NF-κB的激动剂。

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  • Primidone EI2231

    Primidone是活性的iates GABAA 受体 function。

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  • Pregnanolone EI2227

    Pregnanolone是GABAA 受体阳性变构的调节剂（positive allosteric modulator。

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