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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    PSI是蛋白酶体抑制剂，可以抑制NF-κB的激活。

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  • PSN 375963 hydrochloride EI2266

    PSN 375963 hydrochloride是GPR119 受体激动剂。

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  • Psora 4 EI2268

    Psora 4是活性的 KV1.3 通道阻断剂。

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  • PTAC oxalate EI2270

    PTAC oxalate是Muscarinic 受体配体，在其不同的亚型上会展现部分激动或者拮抗的活性。

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  • PTIQ EI2271

    PTIQ是活性MMP-3 激活、表达的抑制剂， 具有神经保护活性。。

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