In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
RP 001 hydrochloride是活性的 S1P1 激动剂。
MoreROS 234 dioxalate是活性的 H3 拮抗剂。
MoreRosmarinic acid是消炎,抑制细胞生长的,抗病毒的活性。也是GPR35的激动剂。
MoreRottlerin是有报道的PKCδ抑制剂。
MoreRo 51是活性的 P2X3, P2X2/3 拮抗剂。
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