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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • Quinidine EI2290

    Quinidine是可以阻断Na, K离子通道。

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  • Quinine hydrochloride EI2291

    Quinine hydrochloride是抗疟活性。

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  • Pyroxamide EI2278

    Pyroxamide是组蛋白去乙酰抑制剂HDAC (histone deacetylase)。

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  • PYZD 4409 EI2280

    PYZD 4409是Ubiquitin-activating enzyme (E1) 的抑制剂。

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  • Pyrrolidinedithiocarbamate ammonium EI2279

    Pyrrolidinedithiocarbamate ammonium是Pyrrolidinedithiocarbamate ammonium inhibits NF-κB and prevents increase in NOS mRNA.。

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