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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • Remacemide hydrochloride EI2319

    Remacemide hydrochloride是Remacemide hydrochloride is a NMDA antagonist，it blocks ion channel and allosteric modulatory site.。

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  • Reversan EI2325

    Reversan是选择性 MRP1，P-gp 抑制剂。

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  • rac BHFF EI2307

    rac BHFF是活性选择性 GABAB 阳性变构的调节剂（positive allosteric modulator）。

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  • Radicicol EI2312

    Radicicol是Hsp90 抑制剂。有抗真菌和抗细菌的活性。。

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  • Ranitidine hydrochloride EI2314

    Ranitidine hydrochloride是选择性 H2 拮抗剂。

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