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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • SB 205384 EI2457

    SB 205384是GABAA受体调节剂（SB 205384 could slow current decay）。

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  • SB 205607 dihydrobromide EI2458

    SB 205607 dihydrobromide是选择性高亲和性非肽类δ1激动剂。

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  • SB 218078 EI2462

    SB 218078是Checkpoint kinase 1 (Chk1)的抑制剂。

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  • Salvinorin A EI2442

    Salvinorin A是高活性的，选择性 κ 激动剂。

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  • Salvinorin B EI2443

    Salvinorin B是可以激活κ-opioid DREADD (KORD)。

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