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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • Ro 01-6128 EI2348

    Ro 01-6128是mGlu1阳性变构的调节剂（positive allosteric modulator）。

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  • Rhosin hydrochloride EI2331

    Rhosin hydrochloride是Rho GTPase inhibitor。

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  • Rifampicin EI2332

    Rifampicin是Pregnane X 的受体激动剂， 抗生素类。

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  • Rifaximin EI2333

    Rifaximin是Pregnane X 受体激动剂， 抗生素类。

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  • Rimcazole dihydrochloride EI2336

    Rimcazole dihydrochloride是σ2 拮抗剂。 也是DAT的抑制剂。

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