In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
RuBi-4AP是化学键和的4-aminopyridine, 是一种非选择性 KV 通道阻断剂。
MoreRuBi-GABA是Ru group bonding GABA that is excitable by visible wavelength。
MoreRSVA 405是AMPK 激动剂, 也是STAT3的抑制剂。
MoreRS 25344 hydrochloride是活性的 PDE4 抑制剂。
MoreRP 001 hydrochloride是活性的 S1P1 激动剂。
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