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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    S26948是选择性 PPARγ 激动剂, 抗糖尿病剂。

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    SA 4503 dihydrochloride是选择性 σ1 受体激动剂。

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    Saclofen是选择性 GABAB 拮抗剂。

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