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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    SBHA是HDAC(Histone deacetylase)抑制剂。

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  • SB 674042 EI2488

    SB 674042是活性选择性非肽类 OX1 拮抗剂。

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  • SB 408124 EI2483

    SB 408124是选择性非肽类 OX1 拮抗剂。

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    SB 239063是活性选择性 p38 MAPK 抑制剂，口服有效。

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