In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
SDZ 220-581是竞争性 NMDA 拮抗剂。
MoreSD 2590 hydrochloride是活性的 MMP 抑制剂。
MoreSCIO 469 hydrochloride是选择性 p38 MAPK抑制剂。
MoreSD 1008是JAK2/STAT3 信号通路的抑制剂。
MoreSCH 50911是选择性, 竞争性口服有效的GABAB 拮抗剂。
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