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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • SEN 12333 EI2531

    SEN 12333是α7 nAChR的激动剂也是 histamine H3的拮抗剂。

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  • SEN 1269 EI2532

    SEN 1269是Amyloid-β aggregation 抑制剂。

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  • SEW 2871 EI2537

    SEW 2871是具有细胞膜通透性的选择性 S1P1 受体激动剂。

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  • SDM25N hydrochloride EI2519

    SDM25N hydrochloride是活性的选择性非肽类 δ 拮抗剂。

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  • SDZ 220-040 EI2522

    SDZ 220-040是活性竞争性 NMDA 拮抗剂。

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