In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
SEW 2871是具有细胞膜通透性的选择性 S1P1 受体激动剂。
MoreSDM25N hydrochloride是活性的选择性非肽类 δ 拮抗剂。
MoreSDZ 220-040是活性竞争性 NMDA 拮抗剂。
MoreSDZ 220-581是竞争性 NMDA 拮抗剂。
MoreSD 2590 hydrochloride是活性的 MMP 抑制剂。
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