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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • TCS PIM-1 1 EI2741

    TCS PIM-1 1是选择性， ATP竞争性Pim-1激酶抑制剂。

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  • TCS HDAC6 20b EI2738

    TCS HDAC6 20b是选择性 HDAC6 抑制剂。

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  • TCS JNK 6o EI2739

    TCS JNK 6o是选择性 JNK 抑制剂。

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  • TCS 46b EI2733

    TCS 46b是口服有效的亚型选择性的NR1A/NR2B拮抗剂。

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  • TCS ERK 11e EI2737

    TCS ERK 11e是活性的，选择性 ERK2 抑制剂。

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