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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    SID 26681509是Cathepsin L 抑制剂。

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  • Siguazodan EI2553

    Siguazodan是PDE3 抑制剂。

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  • SIB 1757 EI2547

    SIB 1757是高选择性mGlu5拮抗剂。

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  • SEN 12333 EI2531

    SEN 12333是α7 nAChR的激动剂也是 histamine H3的拮抗剂。

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  • SEN 1269 EI2532

    SEN 1269是Amyloid-β aggregation 抑制剂。

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