In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
STF 31是NAMPT 抑制剂, 也是GLUT1抑制剂。
MoreS-Sulfo-L-cysteine sodium salt是Group I 激动剂。
MoreSR 95531 hydrobromide是选择性, 竞争性 GABAA 受体拮抗剂。
MoreSR 3576是高 活性的,选择性 JNK3 抑制剂。
MoreSR 3677 dihydrochloride是活性的, 选择性 Rho-kinase (ROCK) 抑制剂。
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