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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • SR 95531 hydrobromide EI2628

    SR 95531 hydrobromide是选择性， 竞争性 GABAA 受体拮抗剂。

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  • SR 3576 EI2619

    SR 3576是高 活性的，选择性 JNK3 抑制剂。

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  • SR 3677 dihydrochloride EI2620

    SR 3677 dihydrochloride是活性的， 选择性 Rho-kinase (ROCK) 抑制剂。

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  • SR 1664 EI2614

    SR 1664是高亲和性 PPARγ 配体， 阻断 Cdk5-dependent PPARγ phosphorylation。

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  • SP 100030 EI2589

    SP 100030是NF-κB，AP-1双效抑制剂。

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