In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
Strontium chloride是Calcium sensing receptor (CaSR)的激动剂。
MoreSU 16f是活性选择性的 PDGFRβ 抑制剂。
MoreSU 3327是选择性 JNK 抑制剂。
MoreSTF 31是NAMPT 抑制剂, 也是GLUT1抑制剂。
MoreS-Sulfo-L-cysteine sodium salt是Group I 激动剂。
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