In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
Tazarotene是具有乙炔维A酸(acetylenic retinoid)受体选择性, 同retinoid acid receptors(RAR)-β和-γ相互作用。
MoreSynthalin sulfate是非竞争性的NMDA 拮抗剂。
MoreT 0156 hydrochloride是高活性选择性的PDE5抑制剂。
MoreSulprostone是EP3和EP1受体的激动剂。
MoreS-Trityl-L-cysteine是Mitotic kinesin Eg5的活性的选择性的抑制剂。
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