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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • TC-E 5006 EI2701

    TC-E 5006是γ-secretase调节剂，降低Aβ42的水平。

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  • TC-G 1001 EI2704

    TC-G 1001是GPR35 激动剂， 相对zaprinast而言活性更强。

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  • TC-E 5005 EI2700

    TC-E 5005是活性选择性 PDE10A 抑制剂。

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  • TC LPA5 4 EI2690

    TC LPA5 4是LPA5 受体拮抗剂。

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  • TB 21007 EI2682

    TB 21007是α5选择性GABAA 反向激动剂。

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