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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • TCN 201 EI2715

    TCN 201是选择性 NR1/NR2A 受体拮抗剂。

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  • TCN 213 EI2716

    TCN 213是NMDA 拮抗剂，对NR2A选择性强于对NR2B。

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  • TC-G 1006 EI2707

    TC-G 1006是活性的，选择性 sphingosine-1-phosphate receptor 1 (S1P1) 激动剂。

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  • TC-H 106 EI2709

    TC-H 106是Class I histone deacetylase(HDAC) 抑制剂。

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  • TC-E 5006 EI2701

    TC-E 5006是γ-secretase调节剂，降低Aβ42的水平。

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