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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • TC-N 22A EI2717

    TC-N 22A是活性选择性mGlu4的阳性变构的调节剂（positive allosteric modulator）。

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  • TCN 237 dihydrochloride EI2718

    TCN 237 dihydrochloride是高活性选择性的NR2B拮抗剂。

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  • TCN 238 EI2719

    TCN 238是mGlu4阳性变构的调节剂（positive allosteric modulator）。

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  • TCN 201 EI2715

    TCN 201是选择性 NR1/NR2A 受体拮抗剂。

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  • TCN 213 EI2716

    TCN 213是NMDA 拮抗剂，对NR2A选择性强于对NR2B。

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