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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • TCS 46b EI2733

    TCS 46b是口服有效的亚型选择性的NR1A/NR2B拮抗剂。

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  • TCS ERK 11e EI2737

    TCS ERK 11e是活性的，选择性 ERK2 抑制剂。

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  • TCS 1205 EI2724

    TCS 1205是亚型选择性GABAA受体激动剂。

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  • TCS 21311 EI2727

    TCS 21311是活性的 JAK3 抑制剂。 也抑制 GSK-3β和PKC。

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  • TCS 3035 EI2730

    TCS 3035是GPR35的激动剂。

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