In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
Telenzepine dihydrochloride是活性选择性 M1 拮抗剂。
MoreTetraethylammonium chloride是非选择性K+通道阻断剂。
MoreTC-SP 14是活性的S1P1受体激动剂。
MoreTCS OX2 29是活性的,选择性 OX2 拮抗剂。
MoreTCS PIM-1 1是选择性, ATP竞争性Pim-1激酶抑制剂。
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