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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    Thiostrepton是抗生素类物质， 抑制protein synthesis。

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    THIP hydrochloride是GABAA激动剂。

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    TFC 007是活性的hematopoietic prostaglandin D synthase (H-PGDS) 抑制剂。

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    TG 4-155是高亲和性，选择性EP2受体拮抗剂。

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