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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • TPMPA EI2803

    TPMPA是选择性GABAA-ρ的拮抗剂。

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  • Tracazolate hydrochloride EI2804

    Tracazolate hydrochloride是亚型选择性的GABAA 的变构的调节剂。

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  • Tramiprosate EI2806

    Tramiprosate是Targets soluble Aβ to decrease amyloid plaque deposition。 也是GABA类似物。

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  • trans-Triprolidine hydrochloride EI2809

    trans-Triprolidine hydrochloride是高活性的经典H1拮抗剂。

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  • TNP-ATP triethylammonium salt EI2792

    TNP-ATP triethylammonium salt是活性的， 选择性 P2X 拮抗剂。

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