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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • U 90042 EI2833

    U 90042是GABAA 受体的配体。

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  • U 93631 EI2834

    U 93631是GABAA 受体的拮抗剂。

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  • TUG 891 EI2823

    TUG 891是活性的，选择性 FFA4 (GPR120) 激动剂。

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  • Tunicamycin EI2824

    Tunicamycin是抗生素类化合物， GlcNAc phosphotransferase的抑制剂。

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  • TWS 119 EI2825

    TWS 119是GSK-3β 抑制剂， induces neuronal differentiation in ESCs。

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