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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    YM 298198 hydrochloride是高活性选择性非竞争性的mGlu1拮抗剂。

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  • YE 120 EI2968

    YE 120是GPR35 激动剂。

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  • YM 230888 EI2973

    YM 230888是选择性mGlu1拮抗剂。

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  • XAP 044 EI2959

    XAP 044是活性的，选择性 mGlu7 拮抗剂。

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  • XE 991 dihydrochloride EI2960

    XE 991 dihydrochloride是活性的， 选择性 KV7 (KCNQ) 通道阻断剂， 可以阻断M电流。

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