In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
UTPγS trisodium salt是选择性 P2Y2/4 激动剂。
MoreUK 78282 hydrochloride是KV1.3,KV1.4 通道的阻断剂。
MoreUDP disodium salt是内源性配体, 是P2Y14 受体的竞争性拮抗剂。
MoreUF 010是Class I HDAC 抑制剂。
MoreUK 356618是活性选择性的MMP-3 抑制剂。
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