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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    VU 0238429是选择性M5受体阳性变构的调节剂（positive allosteric modulator）。

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  • Viomycin EI2885

    Viomycin是抗生素类， 抑制细菌DNA的合成 （bacterial DNA synthesis）。

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  • Vigabatrin EI2883

    Vigabatrin是GABA-T 抑制剂。

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  • UTPγS trisodium salt EI2876

    UTPγS trisodium salt是选择性 P2Y2/4 激动剂。

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  • UK 78282 hydrochloride EI2862

    UK 78282 hydrochloride是KV1.3，KV1.4 通道的阻断剂。

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