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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    VU 0360172 hydrochloride是mGlu5阳性变构的调节剂（positive allosteric modulator）。

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  • VU 0255035 EI2898

    VU 0255035是高选择性muscarinic M1受体的拮抗剂。

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  • VPC 23019 EI2891

    VPC 23019是S1P1的S1P3 拮抗剂。

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  • VU 0155041 EI2893

    VU 0155041是活性的mGlu4阳性变构的调节剂（positive allosteric modulator）。

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  • VU 0155041 sodium salt EI2894

    VU 0155041 sodium salt是活性的mGlu4阳性变构的调节剂（positive allosteric modulator）。

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