In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
α,β-Methyleneadenosine 5'-triphosphate trisodium salt是P2的激动剂。
MoreZM 226600是Kir6 (KATP) 的通道开启剂(channel opener)。
MoreZM 39923 hydrochloride是活性选择性JAK3抑制剂。
MoreZJ 43是Glutamate carboxypeptidase II,III (NAALADase, NAAG peptidase) 抑制剂。
MoreZaprinast是GPR35 激动剂。
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