In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
VU 0155041是活性的mGlu4阳性变构的调节剂(positive allosteric modulator)。
MoreVU 0155041 sodium salt是活性的mGlu4阳性变构的调节剂(positive allosteric modulator)。
MoreVU 0238429是选择性M5受体阳性变构的调节剂(positive allosteric modulator)。
MoreViomycin是抗生素类, 抑制细菌DNA的合成 (bacterial DNA synthesis)。
MoreVigabatrin是GABA-T 抑制剂。
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