Home > 暂无记录 暂无记录 Signal Pathway

Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • Bardoxolone EY2009

    Bardoxolone(RTA 402)是抗氧化炎症调节剂（AIM）的先导化合物。

    More

  • ASP8273 EY2847

    ASP8273 is a small molecule, irreversible TKI inhibitor that inhibits the kinase activity of EGFR mutations including T790M, with limited activity against EGFR wild-type NSCLC. In the in vitro enzymatic and cell-based assays, ASP8273 were evaluated against EGFR mutantsand WT EGFR.

    More

  • EGF-816 EY2846

    EGF816 is a third-generation covalent EGFR inhibitor that has potent inhibitory activity against activating and resistant T790M mutants with low IC50 in various cellular assays.

    More

  • HM-71224 EY2845

    HM-71224 is an EGFR tyrosine kinase inhibitor.

    More

  • Favipiravir EY2835

    Favipiravir是一种有效的选择性RNA-dependent RNA polymerase抑制剂。

    More
    • Current page139, Total Pages360, Total Record1796 First Prev 137138139140141 Next Last Goto
More