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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    (+)-SK&F 10047 hydrochloride是σ1 选择性 激动剂。

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  • (+)-Muscarine iodide EI0067

    (+)-Muscarine iodide是Muscarinic 受体 激动剂。

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  • (+)-Igmesine hydrochloride EI0066

    (+)-Igmesine hydrochloride是选择性 σ1 配体， antidepressant activity。

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  • (+)-Fluprostenol EI0065

    (+)-Fluprostenol是高亲和性 FP prostaglandin 受体 激动剂。

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  • (-)-U-50488 hydrochloride EI0061

    (-)-U-50488 hydrochloride是标准的选择性 κ 激动剂。 是 (±)-U-50488的更有活性的对映体。

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