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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • Z-Cyclopentyl-AP4 EI2988

    Z-Cyclopentyl-AP4是Group III mGlu的激动剂 (mGlu4 > mGlu8 > mGlu7)。

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  • YM 976 EI2978

    YM 976是PDE4抑制剂。

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  • YS-035 hydrochloride EI2980

    YS-035 hydrochloride是抑制 K+ outward/pacemaker电流。

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  • Zamifenacin fumarate EI2983

    Zamifenacin fumarate是选择性 M3 拮抗剂。

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  • YM 298198 hydrochloride EI2975

    YM 298198 hydrochloride是高活性选择性非竞争性的mGlu1拮抗剂。

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