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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • ZJ 43 EI3003

    ZJ 43是Glutamate carboxypeptidase II，III (NAALADase， NAAG peptidase) 抑制剂。

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  • Zaprinast EI2985

    Zaprinast是GPR35 激动剂。

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  • Zardaverine EI2986

    Zardaverine是PDE3/4 抑制剂。

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  • Z-Cyclopentyl-AP4 EI2988

    Z-Cyclopentyl-AP4是Group III mGlu的激动剂 (mGlu4 > mGlu8 > mGlu7)。

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  • YM 976 EI2978

    YM 976是PDE4抑制剂。

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