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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    ZM 226600是Kir6 (KATP) 的通道开启剂（channel opener）。

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  • ZM 39923 hydrochloride EI3013

    ZM 39923 hydrochloride是活性选择性JAK3抑制剂。

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  • ZJ 43 EI3003

    ZJ 43是Glutamate carboxypeptidase II，III (NAALADase， NAAG peptidase) 抑制剂。

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  • Zaprinast EI2985

    Zaprinast是GPR35 激动剂。

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    Zardaverine是PDE3/4 抑制剂。

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