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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    (R)-4-Carboxyphenylglycine是Moderately potent NMDA receptor antagonist.（NMDA受体拮抗剂）。

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  • (R)-(+)-HA-966 EI0119

    (R)-(+)-HA-966是NMDA 部分激动剂/拮抗剂，作用在甘氨酸位点。。

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  • (R)-(-)-α-Methylhistamine dihydrobromide EI0115

    (R)-(-)-α-Methylhistamine dihydrobromide是活性的标准H3 激动剂。

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  • (R)-(-)-Rolipram EI0114

    (R)-(-)-Rolipram是PDE4 抑制剂。 Rolipram的对映体之一。

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  • (R)-(-)-Deprenyl hydrochloride EI0112

    (R)-(-)-Deprenyl hydrochloride是MAO-B 抑制剂。

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