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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • (RS)-APICA EI0137

    (RS)-APICA是选择性 group II 拮抗剂。

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  • (RS)-3，5-DHPG EI0133

    (RS)-3，5-DHPG是选择性group I mGlu激动剂。

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  • (RS)-(Tetrazol-5-yl)glycine EI0131

    (RS)-(Tetrazol-5-yl)glycine是高活性的NMDA受体激动剂。

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  • (R)-DRF053 dihydrochloride EI0127

    (R)-DRF053 dihydrochloride是Dual CK1/cdk 抑制剂。

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  • (R)-CPP EI0125

    (R)-CPP是活性的 NMDA 拮抗剂， (RS)-CPP活性更好的的对映体之一  。

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