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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • (S)-(+)-Dimethindene maleate EI0149

    (S)-(+)-Dimethindene maleate是M2-选择性 拮抗剂。

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  • (S)-(-)-HA-966 EI0146

    (S)-(-)-HA-966是NMDA 拮抗剂/部分激动剂。

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  • (RS)-MCPG EI0141

    (RS)-MCPG是非选择性 mGlu 拮抗剂。

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  • (RS)-CPP EI0140

    (RS)-CPP是活性的 NMDA 拮抗剂。

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  • (RS)-Baclofen EI0139

    (RS)-Baclofen是选择性 GABAB 激动剂。

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