In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
(-)-5'-DMH-CBD是Metabolically stable anandamide transport的抑制剂。
More(-)-[3R,4S]-Chromanol 293B是Delayed rectifier K+ current(Iks)阻断剂。 Chromanol 293B的对映体之一。
MoreAcetazolamide是一种碳酸酐酶(CA)有效抑制剂。
MoreDEL-22379抑制ERK二聚化, IC50=0.5 μM。
MoreLX-4211是SGLT1/2抑制剂,是抗糖尿病剂。
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