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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    1，2，3，4，5，6-Hexabromocyclohexane是抑制 JAK2 自磷酸化。

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  • (S)-SNAP 5114 EI0164

    (S)-SNAP 5114是GABA uptake inhibitor（摄取抑制剂）。

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  • (S)-HexylHIBO EI0161

    (S)-HexylHIBO是Group I mGlu 拮抗剂。

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  • (S)-4-Carboxy-3-hydroxyphenylglycine EI0158

    (S)-4-Carboxy-3-hydroxyphenylglycine是Group I 拮抗剂/group II 激动剂。

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  • (S)-3-Hydroxyphenylglycine EI0157

    (S)-3-Hydroxyphenylglycine是Group I mGlu 激动剂，活性更好的的对映体之一。

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