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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • (±)-LY 395756 EI0089

    (±)-LY 395756是Mixed mGlu2 激动剂/ mGlu3 拮抗剂。

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  • (±)-Clopidogrel hydrochloride EI0079

    (±)-Clopidogrel hydrochloride是选择性 P2Y12 拮抗剂。

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  • (±)-1-(1，2-Diphenylethyl)piperidine maleate EI0073

    (±)-1-(1，2-Diphenylethyl)piperidine maleate是NMDA 拮抗剂，作用于离子通道位点。

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  • (+)-U-50488 hydrochloride EI0071

    (+)-U-50488 hydrochloride是标准选择性 κ 激动剂。 是 (±)-U-50488 的较弱活性的对映体之一。

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  • (+)-SK&F 10047 hydrochloride EI0069

    (+)-SK&F 10047 hydrochloride是σ1 选择性 激动剂。

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