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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • (±)-PPCC oxalate EI0097

    (±)-PPCC oxalate是Selective sigma (σ) 激动剂 (σ1> σ2)。

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  • (±)-Nipecotic acid EI0094

    (±)-Nipecotic acid是GABA uptake inhibitor（摄取抑制剂）。

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  • (±)-LY 395756 EI0089

    (±)-LY 395756是Mixed mGlu2 激动剂/ mGlu3 拮抗剂。

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  • (±)-Clopidogrel hydrochloride EI0079

    (±)-Clopidogrel hydrochloride是选择性 P2Y12 拮抗剂。

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  • (±)-1-(1，2-Diphenylethyl)piperidine maleate EI0073

    (±)-1-(1，2-Diphenylethyl)piperidine maleate是NMDA 拮抗剂，作用于离子通道位点。

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