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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • (1R，1'S，3'R/1R，1'R，3'S)-L-054，264 EI0104

    (1R，1'S，3'R/1R，1'R，3'S)-L-054，264是活性的，选择性 sst2 激动剂。

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  • (±)-U-50488 hydrochloride EI0102

    (±)-U-50488 hydrochloride是标准选择性 κ 激动剂。

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  • (±)-trans-ACPD EI0101

    (±)-trans-ACPD是Group I/group II mGlu 激动剂。

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  • (±)-PPCC oxalate EI0097

    (±)-PPCC oxalate是Selective sigma (σ) 激动剂 (σ1> σ2)。

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  • (±)-Nipecotic acid EI0094

    (±)-Nipecotic acid是GABA uptake inhibitor（摄取抑制剂）。

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