In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
(R)-(-)-Rolipram是PDE4 抑制剂。 Rolipram的对映体之一。
More(R)-(-)-Deprenyl hydrochloride是MAO-B 抑制剂。
More(2R,4R)-APDC是高选择性 group II 激动剂。
More(2R,3S)-Chlorpheg是弱效的NMDA拮抗剂。
More(1S,3R)-ACPD是Group I/group II mGlu 激动剂。
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