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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    (2R,3S)-Chlorpheg是弱效的NMDA拮抗剂。

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    (1S,3R)-ACPD是Group I/group II mGlu 激动剂。

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    (1R,1'S,3'R/1R,1'R,3'S)-L-054,264是活性的,选择性 sst2 激动剂。

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  • (±)-U-50488 hydrochloride EI0102

    (±)-U-50488 hydrochloride是标准选择性 κ 激动剂。

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  • (±)-trans-ACPD EI0101

    (±)-trans-ACPD是Group I/group II mGlu 激动剂。

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