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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • 5，7-Dichlorokynurenic acid sodium salt EI0287

    5，7-Dichlorokynurenic acid sodium salt是 5，7-Dichlorokynurenic acid的钠盐。活性的 NMDA 拮抗剂，作用于甘氨酸位点。

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  • 4-P-PDOT EI0286

    4-P-PDOT是MT2 拮抗剂。

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  • 4-PPBP maleate EI0285

    4-PPBP maleate是特异性 σ 配体， NMDA 拮抗剂。

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  • 4-Methylhistamine dihydrochloride EI0283

    4-Methylhistamine dihydrochloride是选择性， 高亲和性 H4 激动剂。

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  • 4-IBP EI0281

    4-IBP是σ 配体， σ1 > σ2。

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