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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • (S)-4-Carboxy-3-hydroxyphenylglycine EI0158

    (S)-4-Carboxy-3-hydroxyphenylglycine是Group I 拮抗剂/group II 激动剂。

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  • (S)-3-Hydroxyphenylglycine EI0157

    (S)-3-Hydroxyphenylglycine是Group I mGlu 激动剂，活性更好的的对映体之一。

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  • (S)-3，5-DHPG EI0156

    (S)-3，5-DHPG是选择性 group I mGlu 激动剂。3，5-DHPG 的活性更好的的对映体之一 。

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  • (S)-3，4-DCPG EI0155

    (S)-3，4-DCPG是活性的， 选择性 mGlu8a 激动剂。

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  • (S)-(+)-α-Methylhistamine dihydrobromide EI0154

    (S)-(+)-α-Methylhistamine dihydrobromide是H3 激动剂，较弱活性的对映体。

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