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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • A 740003 EI0333

    A 740003是活性的，选择性 P2X7 拮抗剂。

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  • A 331440 dihydrochloride EI0325

    A 331440 dihydrochloride是选择性 H3 拮抗剂。

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  • A 1070722 EI0322

    A 1070722是高 活性的， 选择性 GSK-3 抑制剂。

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  • 8-pCPT-2-O-Me-cAMP-AM EI0319

    8-pCPT-2-O-Me-cAMP-AM是选择性 Epac 激动剂， cell-permeable 8CPT-2Me-cAMP 的类似物。

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  • 8-Bromo-cAMP， sodium salt EI0312

    8-Bromo-cAMP， sodium salt是Cell-permeable cAMP 类似物。

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