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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • 17-PA EI0217

    17-PA是Neurosteroid activation的拮抗剂，direct gating of GABAA。

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  • 16，16-Dimethyl Prostaglandin E2 EI0215

    16，16-Dimethyl Prostaglandin E2是Synthetic prostaglandin E2 derivative， regulates HSC development。

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  • 10Z-Hymenialdisine EI0213

    10Z-Hymenialdisine是广谱激酶抑制剂， 高活性抑制 MEK1。

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  • 10-DEBC hydrochloride EI0212

    10-DEBC hydrochloride是选择性 Akt/PKB 抑制剂。

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  • 1，2，3，4，5，6-Hexabromocyclohexane EI0209

    1，2，3，4，5，6-Hexabromocyclohexane是抑制 JAK2 自磷酸化。

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