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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • 2-Arachidonylglycerol EI0237

    2-Arachidonylglycerol是内源性 cannabinoid 激动剂， 活性的 GPR55 激动剂。

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  • 1-Oleoyl lysophosphatidic acid sodium salt EI0226

    1-Oleoyl lysophosphatidic acid sodium salt是LPA1 和 LPA2的内源性激动剂。

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  • 1-EBIO EI0223

    1-EBIO是Epithelial KCa离子通道的激动剂。

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  • 17-PA EI0217

    17-PA是Neurosteroid activation的拮抗剂，direct gating of GABAA。

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  • 16，16-Dimethyl Prostaglandin E2 EI0215

    16，16-Dimethyl Prostaglandin E2是Synthetic prostaglandin E2 derivative， regulates HSC development。

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