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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • 2-Iodomelatonin EI0246

    2-Iodomelatonin是高亲和性 melatonin 激动剂。

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  • 2-Hydroxysaclofen EI0244

    2-Hydroxysaclofen是选择性 GABAB 拮抗剂，比saclofen活性更强。。

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  • 2-Arachidonylglycerol EI0237

    2-Arachidonylglycerol是内源性 cannabinoid 激动剂， 活性的 GPR55 激动剂。

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  • 1-Oleoyl lysophosphatidic acid sodium salt EI0226

    1-Oleoyl lysophosphatidic acid sodium salt是LPA1 和 LPA2的内源性激动剂。

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  • 1-EBIO EI0223

    1-EBIO是Epithelial KCa离子通道的激动剂。

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