In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
2-Phenylmelatonin是活性的 melatonin 激动剂。
More2-MPPA是选择性 glutamate carboxypeptidase II (GCP II) 抑制剂, 口服有效。
More2-MPMDQ是活性的, 选择性 α1 拮抗剂。也是σ2 配体。
More2-Methylthioadenosine triphosphate tetrasodium salt是P2 purinergic agonist。
More2-Methylthioadenosine diphosphate trisodium salt是P2Y1, P2Y12 和 P2Y13活性的激动剂。
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