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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    3-Cyano-7-ethoxycoumarin是Fluorescent cytochrome P450 substrate。

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    2-ThioUTP tetrasodium salt是活性的,选择性 P2Y2 激动剂。

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    2-Pyridylethylamine dihydrochloride是H1 受体 激动剂。

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    2-Phenylmelatonin是活性的 melatonin 激动剂。

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    2-MPPA是选择性 glutamate carboxypeptidase II (GCP II) 抑制剂, 口服有效。

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