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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    4-IBP是σ 配体, σ1 > σ2。

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  • 4-HQN EI0280

    4-HQN是PARP 抑制剂。

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  • 4-DAMP EI0278

    4-DAMP是Muscarinic M3 拮抗剂。

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  • 4-Aminopyridine EI0275

    4-Aminopyridine是非选择性voltage-dependent K+通道阻断剂。

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  • 4,4-Pentamethylenepiperidine hydrochloride EI0273

    4,4-Pentamethylenepiperidine hydrochloride是M2 proton 通道阻断剂。

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