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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    AMG 548是活性的，选择性 p38α 抑制剂。

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  • AM 92016 hydrochloride EI0427

    AM 92016 hydrochloride是KV 通道阻断剂。

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  • AM 1172 EI0423

    AM 1172是Anandamide uptake inhibitor（摄取抑制剂）， 也是FAAH 抑制剂，CB 受体部分激动剂。

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    Alphaxalone是直接激动剂， 加强GABAA受体激动的膜电流。

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    Allopregnanolone是GABAA受体阳性变构调节剂。

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