In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
7-Chlorokynurenic acid是活性的竞争性的L-glutamate uptake inhibitor (摄取抑制剂)。
More6'-GNTI dihydrochloride是选择性 κ/δ opioid heterodimer 受体激动剂。
More6-Chloromelatonin是Melatonin 激动剂。
More5-OMe-UDP trisodium salt是活性的 P2Y6 激动剂。
More5-Methylfurmethiodide是活性的 muscarinic 激动剂。
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