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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    Adaphostin是p210bcr/abl 激酶抑制剂。

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    ACPT-II是竞争性 mGlu 受体拮抗剂。

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    ACPT-I是Group III mGlu 激动剂。

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    ACDPP hydrochloride是选择性 mGlu5 受体拮抗剂。

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