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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    BD 1063 dihydrochloride是选择性 σ1 配体， 拮抗剂。

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  • BD 1047 dihydrobromide EI0543

    BD 1047 dihydrobromide是σ1 选择性拮抗剂。

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  • BD 1008 dihydrobromide EI0542

    BD 1008 dihydrobromide是活性的， 选择性 σ 配体。

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  • BC 11-38 EI0541

    BC 11-38是选择性 PDE11 抑制剂。

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  • BAY-u 9773 EI0537

    BAY-u 9773是CysLT1 和 CysLT2 拮抗剂。

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